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Drugs in development · updated 30 October 2026

Meningioma: drugs in development

Rare diseasePrevalence 1-9 / 100 000 according to Orphanet · ORPHA:2495

As of 30 October 2026 there are 32 active clinical trials (recruiting or ongoing, phases I–III) on 33 drugs for meningioma. 12 are experimental, that is not yet approved in the United States.

32Active trials
12Experimental drugs
0Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
LuvometinibFCN-159I–II2NCT07708285
SerplulimabHLX10, Hetronifly®I–II2NCT07708285
177Lu-DOTA-JR11I–II1NCT04997317
177Lu-DOTATOCLutetium Lu 177-EdotreotideI–II1NCT04997317
JZP3507II1NCT07533942
L-lysineI–II1NCT07150806
VistusertibAZD2014II1NCT03071874
ZanzalintinibXL092II1NCT07428616
DalpiciclibDalpicilib, DalpciclibI1NCT07652762
IfebemtinibIN10018I1NCT07652762
ONC206I1NCT04541082
18-FDGEarly I1NCT06632860

Sorted by most advanced phase and number of active trials.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
LutatheraLutetium Lu 177 Dotatate, 177Lu-DOTATATEI–II6NCT05278208
AbemaciclibLY2835219, Verzenio®II3NCT02523014
PembrolizumabKEYTRUDA, MK-3475I–II3NCT06640582
IpilimumabYERVOY, ipililumab IVI–II2NCT03604978
NivolumabOpdivo, ONO-4538I–II2NCT03604978
SelumetinibAZD6244, Koselugo®II2NCT07707947
Bevacizumabavastin, MVASIII1NCT04374305
BrigatinibAlunbrig®II1NCT04374305
CabozantinibResniben®, Cabometyx®II1NCT05425004
CapivasertibAZD5363, Truqap®II1NCT02523014
CeritinibZykadia®II1NCT07893197
CyclophosphamideCyclophosphamid, CytoxanI–II1NCT06640582
DexamethasoneDexametasone, DextenzaII1NCT06132685
EverolimusRAD001, EveroliumusII1NCT06126588
FludarabineFludara, FLUDARABINI–II1NCT06640582

Sorted by most advanced phase and number of active trials. Showing 15 of 21 drugs.

All 33 drugs, with the details

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Broader categories

Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D008579 “Meningioma”. Prevalence: Orphanet.

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