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Drugs in development · updated 30 October 2026

Luvometinib: clinical trials and development status

Other names and codes: FCN-159

FDA substance registryNot approved in the USNo EMA authorisationEstimated launch Jun 2028 – Apr 2029 (Phuturdex estimate)

As of 30 October 2026 Luvometinib is in 10 active clinical trials (recruiting or ongoing, phases I–III) for 9 diseases. The most advanced phase is III.

10Active trials
IIIMost advanced phase
9Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Luvometinib and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Langerhans-cell histiocytosisII2NCT07728201
MeningiomaII2NCT07713745
Neurofibromatosis 1I–II2NCT07024394
Neurofibromatosis 2II2NCT07713745
Neuroma, AcousticII2NCT07713745
Plexiform neurofibromaI–II2NCT07024394
EpendymomaII1NCT07713745
MetastasisII1NCT07562581
Nerve sheath neoplasmsII1NCT06553365

Everything on Luvometinib

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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