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Drugs in development · updated 30 October 2026

Gingivitis: drugs in development

As of 30 October 2026 there are 6 active clinical trials (recruiting or ongoing, phases I–III) on 5 drugs for gingivitis. 2 are experimental, that is not yet approved in the United States.

6Active trials
2Experimental drugs
2Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
MeridolIII1NCT07842978
XylitolD-xylitolII–III1NCT07424846

Sorted by most advanced phase and number of active trials.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
ChlorhexidineReadyprep Chg®, Periochip®III2NCT07401069
Sodium BicarbonateSodium Bicarbonate In Plastic Container®III1NCT07842991
Povidone-IodinePovidon-iodine, Providone-IodineII1NCT06616207

Sorted by most advanced phase and number of active trials.

All 5 drugs, with the details

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Broader categories

Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D005891 “Gingivitis”.

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