Phuturdex › Diseases › Heart Failure, Diastolic
Drugs in development · updated 30 October 2026
Heart Failure, Diastolic: drugs in development
As of 30 October 2026 there are 4 active clinical trials (recruiting or ongoing, phases I–III) on 4 drugs for heart Failure, Diastolic. 4 are experimental, that is not yet approved in the United States.
Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.
Sign in free →Experimental drugs
Not yet approved by the US FDA for any indication.
| Drug | Most advanced phase | Active trials | Reference trial |
|---|---|---|---|
| Henggliflozin | I–II | 1 | NCT07687212 |
| JK07 | II | 1 | NCT06369298 |
| LY3971297 | I | 1 | NCT07547540 |
| SERCA2a | I | 1 | NCT06061549 |
Sorted by most advanced phase and number of active trials.
All 4 drugs, with the details
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Open in Phuturdex →Broader categories
- Cardiovascular disease 71 drugs
- Heart disease 17 drugs
- Heart failure 104 drugs
- Arrhythmias, Cardiac 10 drugs
Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: NLM MeSH; NLM MeSH term: D054144 “Heart Failure, Diastolic”.