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Drugs in development · updated 30 October 2026

Infertility: drugs in development

As of 30 October 2026 there are 19 active clinical trials (recruiting or ongoing, phases I–III) on 24 drugs for infertility. 5 are experimental, that is not yet approved in the United States.

19Active trials
5Experimental drugs
3Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
Human chorionic gonadotropinHuman chorionic gonadotrophinIII2NCT05586802
FertiloIII1NCT06858111
UtrogestanIII1NCT07738068
Follitropin deltaREKOVELLEII1NCT07153367
Follicle Stimulating HormoneI1NCT06414096

Sorted by most advanced phase and number of active trials.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
ProgesteroneMilprosa®, Endometrin®III3NCT07340827
Cetrorelix acetateCetrotide®III2NCT07340827
Letrozoleoral FemaraIII2NCT03011684
TamoxifenSoltamox®, Nolvadex®III2NCT03011684
AnastrozoleAnastrozol, AnastrazoleIII1NCT05586802
Clomiphene CitrateSerophene®, Clomid®III1NCT07616973
DHEAdehydroepiandrosterone, PrasteroneII–III1NCT07323329
DydrogesteroneGynorest®III1NCT03859921
ElagolixOrilissa®III1NCT06375811
Folic acidQuiofic®, Folvite®II–III1NCT07323329
Megestrol AcetateMegace Es®, Megace®II–III1NCT05316493
Pentoxifyllinepentoxyifylline, Trental®III1NCT07499817
Recombinant Human Growth Hormone InjectionSomatropin, Human Growth HormoneII–III1NCT07323329
SemaglutideWegovy, RybelsusIII1NCT05586802
TestosteroneNatesto®, Vogelxo®III1NCT05586802

Sorted by most advanced phase and number of active trials. Showing 15 of 19 drugs.

All 24 drugs, with the details

In Phuturdex every drug has all its trials, sponsors and countries, FDA and EMA approvals, orphan designations and safety alerts. Free until 31 March 2027.

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Specific forms

Broader categories

Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D007246 “Infertility”.

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