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Drugs in development · updated 30 October 2026

Pentoxifylline: clinical trials and development status

Other names and codes: Trental

NLM verified identityApproved in the US (FDA)

As of 30 October 2026 Pentoxifylline is in 14 active clinical trials (recruiting or ongoing, phases I–III) for 15 diseases. The most advanced phase is III.

14Active trials
IIIMost advanced phase
15Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Pentoxifylline and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Chronic renal insufficiencyIII2NCT05284656
Bisphosphonate-associated osteonecrosis of the jawIII1NCT03040778
InfertilityIII1NCT07499817
Irritable bowel syndromeIII1NCT04217733
OsteonecrosisIII1NCT03040778
Sexually transmitted infectionII–III1NCT05897034
FibrosisII2NCT06494111
LymphedemaII2NCT06494111
Chronic kidney failureI–II1NCT06903689
EpilepsyII1NCT05637086
Head and neck neoplasmsII1NCT06912763
Inflammatory bowel diseasesII1NCT07349472
Non-small-cell lung carcinomaII1NCT06634056
Rheumatoid arthritisII1NCT06998628
Vascular calcificationI–II1NCT06903689

Everything on Pentoxifylline

In Phuturdex you get every trial with sponsors, countries and dates, development events, FDA and EMA approvals, patents and exclusivities, orphan designations and safety alerts, with PDF and Excel export. Free until 31 March 2027.

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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