Phuturdex › Diseases › Inflammatory bowel diseases
Drugs in development · updated 30 October 2026
Inflammatory bowel diseases: drugs in development
As of 30 October 2026 there are 55 active clinical trials (recruiting or ongoing, phases I–III) on 69 drugs for inflammatory bowel diseases. 41 are experimental, that is not yet approved in the United States.
Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.
Sign in free →Experimental drugs
Not yet approved by the US FDA for any indication.
Sorted by most advanced phase and number of active trials. Showing 40 of 41 drugs.
Approved drugs in new trials
Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.
| Drug | Most advanced phase | Active trials | Reference trial |
|---|---|---|---|
| MirikizumabOmvoh® | III | 4 | NCT05509777 |
| DexmedetomidineIgalmi®, Precedex® | III | 1 | NCT07434310 |
| FluconazoleDiflucan®, Diflucan In Dextrose 5% In Plastic Container® | III | 1 | NCT06274554 |
| GuselkumabTremfya | III | 1 | NCT05923073 |
| ModafinilProvigil® | II–III | 1 | NCT07582458 |
| Mesalaminemesalazine, Delzicol® | I–II | 2 | NCT05119140 |
| VedolizumabEntyvio® | II | 2 | NCT03219359 |
| AlemtuzumabCampath, Lemtrada® | II | 1 | NCT01962415 |
| AmitriptylineElavil® | II | 1 | NCT06261320 |
| CyclophosphamideCyclophosphamid, Cytoxan | II | 1 | NCT03219359 |
| DuloxetineDrizalma Sprinkle®, Cymbalta® | II | 1 | NCT07431606 |
| FludarabineFludara, FLUDARABIN | II | 1 | NCT01962415 |
| HydroxychloroquineSovuna®, Plaquenil® | I–II | 1 | NCT05119140 |
| HydroxyureaHydroxycarbamide, Hydroxycarbamid | II | 1 | NCT01962415 |
| InfliximabZymfentra®, Avsola® | II | 1 | NCT06453317 |
Sorted by most advanced phase and number of active trials. Showing 15 of 28 drugs.
All 69 drugs, with the details
In Phuturdex every drug has all its trials, sponsors and countries, FDA and EMA approvals, orphan designations and safety alerts. Free until 31 March 2027.
Open in Phuturdex →Specific forms
- Ulcerative colitis 99 drugs
- Crohn's disease 81 drugs
- Colitis 24 drugs
- Obesity 233 drugs
- Overweight 139 drugs
- Sclerosing cholangitis 17 drugs
- Psoriatic arthritis 48 drugs
- Ulcer 9 drugs
- Inflammation 85 drugs
- Renal cell carcinoma 228 drugs
- Non-small-cell lung carcinoma 726 drugs
- Melanoma 352 drugs
Broader categories
- Intestinal disease 15 drugs
- Gastroenteritis 4 drugs
- Digestive System Diseases 36 drugs
- Gastrointestinal disease 22 drugs
- Colonic disease 11 drugs
- Colitis 24 drugs
Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D015212 “Inflammatory Bowel Diseases”.