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Drugs in development · updated 30 October 2026

Guselkumab: clinical trials and development status

Other names and codes: Tremfya

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 10 November 2017

As of 30 October 2026 Guselkumab is in 23 active clinical trials (recruiting or ongoing, phases I–III) for 24 diseases. The most advanced phase is III.

23Active trials
IIIMost advanced phase
24Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Guselkumab and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Crohn's diseaseIII8NCT07577843
Ulcerative colitisIII6NCT07577856
Psoriatic arthritisIII4NCT04882098
Arthritis, JuvenileIII2NCT06663332
Allergic contact dermatitisII–III1NCT05535738
DermatitisII–III1NCT05535738
Inflammatory bowel diseasesIII1NCT05923073
PsoriasisIII1NCT03451851
Ankylosing spondylitisII1NCT07138898
DermatomyositisII1NCT07138898
Giant cell arteritisII1NCT07138898
Granulomatosis with polyangiitisII1NCT07138898
Pemphigus, Benign FamilialII1NCT06651489
Polymyalgia rheumaticaII1NCT07138898
PolymyositisII1NCT07138898
PyodermaII1NCT06563323
Pyoderma gangrenosumII1NCT06563323
Rheumatic DiseasesII1NCT07138898
Rheumatoid arthritisII1NCT07138898
Skin diseaseII1NCT06563323
SpondylarthritisII1NCT07138898
Systemic lupus erythematosusII1NCT07138898
UlcerII1NCT06563323
VasculitisII1NCT07138898

Everything on Guselkumab

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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