Phuturdex › Diseases › Inflammation
Drugs in development · updated 30 October 2026
Inflammation: drugs in development
As of 30 October 2026 there are 98 active clinical trials (recruiting or ongoing, phases I–III) on 85 drugs for inflammation. 36 are experimental, that is not yet approved in the United States.
Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.
Sign in free →Experimental drugs
Not yet approved by the US FDA for any indication.
Sorted by most advanced phase and number of active trials.
Approved drugs in new trials
Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.
| Drug | Most advanced phase | Active trials | Reference trial |
|---|---|---|---|
| ColchicineColchicin, Lodoco® | II–III | 12 | NCT07571681 |
| AnakinraKINERET | III | 3 | NCT07371689 |
| AtorvastatinLipitor, Atorvaliq® | II–III | 3 | NCT04147286 |
| KetorolacAcuvail®, Sprix® | III | 2 | NCT06968806 |
| MetforminRiomet Er®, Glumetza® | III | 2 | NCT04511416 |
| PrednisolonePrednisolon, Prenisolone | II–III | 2 | NCT07571681 |
| CelecoxibCelebrex Capsule, Elyxyb® | III | 1 | NCT05644301 |
| ChlorhexidineReadyprep Chg®, Periochip® | III | 1 | NCT06489431 |
| DexamethasoneDexametasone, Dextenza | III | 1 | NCT05895838 |
| GentamicinGentamicine, Garamycin® | III | 1 | NCT06489431 |
| Icosapent ethylVascepa®, Vazkepa® | III | 1 | NCT06710080 |
| MinocyclineMinocyclin, Emrosi® | III | 1 | NCT05644301 |
| OlanzapineWeltruza®, Zyprexa Relprevv® | III | 1 | NCT05895838 |
| RifampicinRifampin, RIFADIN | III | 1 | NCT06489431 |
| RifaximinXifaxan® | II–III | 1 | NCT05587036 |
Sorted by most advanced phase and number of active trials. Showing 15 of 49 drugs.
All 85 drugs, with the details
In Phuturdex every drug has all its trials, sponsors and countries, FDA and EMA approvals, orphan designations and safety alerts. Free until 31 March 2027.
Open in Phuturdex →Specific forms
- Sepsis 48 drugs
- Septic shock 26 drugs
- Cytokine release syndrome 21 drugs
- Neuroinflammatory diseases 15 drugs
- Critical illness 19 drugs
- Infection 71 drugs
- Multiple myeloma 272 drugs
- Acute respiratory distress syndrome 43 drugs
- Amyotrophic lateral sclerosis 79 drugs
- Neonatal sepsis 3 drugs
- Bacteremia 8 drugs
- Community-acquired pneumonia 45 drugs
Broader categories
- Cardiovascular disease 71 drugs
- Vascular disease 16 drugs
- Nervous System Diseases 39 drugs
- Brain Diseases 23 drugs
- Central nervous system disease 38 drugs
- Nutritional and metabolic diseases 5 drugs
Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D007249 “Inflammation”.