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Drugs in development · updated 30 October 2026

Minocycline: clinical trials and development status

Other names and codes: Emrosi, Zilxi, Amzeeq, Minolira

NLM verified identityApproved in the US (FDA)

As of 30 October 2026 Minocycline is in 18 active clinical trials (recruiting or ongoing, phases I–III) for 27 diseases. The most advanced phase is III.

18Active trials
IIIMost advanced phase
27Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Minocycline and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Ischemic strokeIII4NCT07526987
Cerebral hemorrhageIII2NCT07338175
Brain infarctionII–III1NCT07594314
Chronic arterial occlusive diseaseII–III1NCT07594301
Helicobacter infectionIII1NCT07904429
Hemorrhagic strokeII–III1NCT07237048
InflammationIII1NCT05644301
Major depressive disorderIII1NCT05644301
NeurosyphilisIII1NCT07904533
Retinal diseaseIII1NCT07082855
Retinitis pigmentosaIII1NCT07082855
Rheumatoid arthritisIII1NCT03414502
StrokeII–III1NCT07237048
GlioblastomaII1NCT07735819
Intracranial vasospasmII1NCT04876638
Non-small-cell lung carcinomaII1NCT06120140
Pancreatic neoplasmII1NCT07895498
Retinal degenerationI–II1NCT05474729
Ruptured aneurysmII1NCT04876638
Traumatic brain injuryII1NCT05826912
UveitisI–II1NCT05474729
Cognition DisordersI1NCT05605366
Cognitive dysfunctionI1NCT05605366
Neuroinflammatory diseasesI1NCT05605366
Sickle-cell diseaseI1NCT05605366
PeriodontitisEarly I1NCT07298057
Type 2 diabetesEarly I1NCT07298057

Everything on Minocycline

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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