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Drugs in development · updated 30 October 2026

Community-acquired pneumonia: drugs in development

As of 30 October 2026 there are 20 active clinical trials (recruiting or ongoing, phases I–III) on 45 drugs for community-acquired pneumonia. 8 are experimental, that is not yet approved in the United States.

20Active trials
8Experimental drugs
5Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
DMX-200III1NCT02735707
EritoranIII1NCT02735707
MolnupiravirLagevrio®III1NCT04381936
SotrovimabVIR-7831, Xevudy®III1NCT04381936
TrimodulinIII1NCT05722938
NRICM102II1NCT07583992
SR1375II1NCT06577558
OPT101I1NCT06669403

Sorted by most advanced phase and number of active trials.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
MethylprednisoloneMethylprednisolon, MethylprenisoloneIII4NCT07152600
Amoxicillinamoxycillin, Moxatag®II–III3NCT03031210
LevofloxacinLevaquin®, Iquix®II–III3NCT07843017
AnakinraKINERETIII2NCT04381936
AspirinVazalore®, Durlaza®III2NCT04381936
Baloxavir MarboxilXofluza®III2NCT04381936
BaricitinibOlumiant®III2NCT04381936
ClarithromycinBiaxin Xl®, Biaxin®III2NCT07834346
HydroxychloroquineSovuna®, Plaquenil®III2NCT04381936
OseltamivirTamiflu®, Ebilfumin®III2NCT04381936
TocilizumabTociluzumab, AvtozmaIII2NCT04381936
AcyclovirSitavig®, Avaclyr®III1NCT06134492
ApremilastOtezla, Apremilast Accord®III1NCT02735707
AzithromycinAzasite®, Zithromax®III1NCT04381936
Ceftaroline fosamilCeftaroline, Teflaro®III1NCT02735707

Sorted by most advanced phase and number of active trials. Showing 15 of 37 drugs.

All 45 drugs, with the details

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Broader categories

Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D000098968 “Community-Acquired Pneumonia”.

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