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Drugs in development · updated 30 October 2026

Hydroxychloroquine: clinical trials and development status

Other names and codes: Sovuna, Plaquenil

NLM verified identityApproved in the US (FDA)

As of 30 October 2026 Hydroxychloroquine is in 42 active clinical trials (recruiting or ongoing, phases I–III) for 54 diseases. The most advanced phase is III.

42Active trials
IIIMost advanced phase
54Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Hydroxychloroquine and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov. Showing 30 of 54 diseases.

DiseaseMost advanced phaseActive trialsReference trial
COVID-19III3NCT04381936
Community-acquired pneumoniaIII2NCT04381936
PneumoniaIII2NCT04381936
Rheumatoid arthritisIII2NCT03414502
Systemic lupus erythematosusIII2NCT05799378
InfluenzaIII1NCT02735707
Lung diseaseIII1NCT02735707
MyocarditisII–III1NCT05961202
Pre-eclampsiaIII1NCT05287321
Respiratory diseaseIII1NCT02735707
Respiratory tract infectionIII1NCT02735707
Rheumatic feverIII1NCT07830108
Rheumatic heart diseaseIII1NCT07830108
Breast neoplasmII3NCT07825454
MelanomaII3NCT07750067
ArthralgiaII2NCT04354649
ArthritisII2NCT04354649
Colorectal neoplasmII2NCT05843188
Interstitial lung diseaseII2NCT07443436
Ovarian neoplasmII2NCT06971744
Pancreatic neoplasmII2NCT05733000
Adenocarcinoma of the lungII1NCT05733000
Ankylosing spondylitisII1NCT07138898
Arthritis, JuvenileII1NCT07138898
ChondrocalcinosisII1NCT06768294
DermatomyositisII1NCT07138898
Discoid lupus erythematosusII1NCT07557927
Dry eye syndromeII1NCT05113004
Giant cell arteritisII1NCT07138898
GliomaI–II1NCT04201457

Everything on Hydroxychloroquine

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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