Phuturdex › Diseases › Dry eye syndrome
Drugs in development · updated 30 October 2026
Dry eye syndrome: drugs in development
As of 30 October 2026 there are 14 active clinical trials (recruiting or ongoing, phases I–III) on 18 drugs for dry eye syndrome. 12 are experimental, that is not yet approved in the United States.
Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.
Sign in free →Experimental drugs
Not yet approved by the US FDA for any indication.
| Drug | Most advanced phase | Active trials | Reference trial |
|---|---|---|---|
| CAM-101 | III | 1 | NCT06903611 |
| Licaminlimab | II–III | 1 | NCT07548632 |
| BL1107 | II | 1 | NCT07778888 |
| DFL24498 | II | 1 | NCT07503886 |
| TJO-087 | II | 1 | NCT07810972 |
| VSJ-110 | II | 1 | NCT07179055 |
| ABBV-319 | I | 1 | NCT06977724 |
| BMS-986553 | I | 1 | NCT07873931 |
| Optive | I | 1 | NCT06375343 |
| PRO-190 | I | 1 | NCT06379685 |
| PRO-240 | I | 1 | NCT06375343 |
| JN002 | Early I | 1 | NCT07245017 |
Sorted by most advanced phase and number of active trials.
Approved drugs in new trials
Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.
| Drug | Most advanced phase | Active trials | Reference trial |
|---|---|---|---|
| BlinatumomabBlincyto® | II | 1 | NCT07852234 |
| HydroxychloroquineSovuna®, Plaquenil® | II | 1 | NCT05113004 |
| InfliximabZymfentra®, Avsola® | II | 1 | NCT07671222 |
| LeflunomideArava®, Leflunomide Zentiva (previously Leflunomide Winthrop)® | II | 1 | NCT05113004 |
| Loteprednol | II | 1 | NCT07671222 |
| Mycophenolate MofetilMycophenolate, Cellcept | II | 1 | NCT05113004 |
Sorted by most advanced phase and number of active trials.
All 18 drugs, with the details
In Phuturdex every drug has all its trials, sponsors and countries, FDA and EMA approvals, orphan designations and safety alerts. Free until 31 March 2027.
Open in Phuturdex →Specific forms
- Sjogren's Syndrome 29 drugs
- Systemic lupus erythematosus 178 drugs
- Systemic scleroderma 77 drugs
- Autoimmune disease 94 drugs
- Rheumatoid arthritis 130 drugs
- Myositis 42 drugs
- Anti-neutrophil cytoplasmic antibody-associated vasculitis 35 drugs
- Psoriasis 46 drugs
- Psoriatic arthritis 48 drugs
- Xerostomia 4 drugs
- Inflammation 85 drugs
- Crohn's disease 81 drugs
Broader categories
- Eye disease 19 drugs
- Skin and connective tissue diseases 3 drugs
- Immune System Diseases 54 drugs
- Connective tissue disease 21 drugs
- Joint Diseases 6 drugs
- Musculoskeletal disorder 22 drugs
Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D015352 “Dry Eye Syndromes”.