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Drugs in development · updated 30 October 2026

Pneumonia: drugs in development

As of 30 October 2026 there are 26 active clinical trials (recruiting or ongoing, phases I–III) on 63 drugs for pneumonia. 14 are experimental, that is not yet approved in the United States.

26Active trials
14Experimental drugs
9Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
IbuzatrelvirIII2NCT06679140
PCV20III2NCT07425392
DMX-200III1NCT02735707
EritoranIII1NCT02735707
GBS-NNII–III1NCT06592586
KetofolIII1NCT07530146
MolnupiravirLagevrio®III1NCT04381936
SotrovimabVIR-7831, Xevudy®III1NCT04381936
VaxigripIII1NCT07604103
AgenT-797II1NCT07615010
AV-001II1NCT05123755
EfzofitimodII1NCT05892614
MelatoninSlenyto®, Circadin®I–II1NCT06949904
VerekitugII1NCT06981078

Sorted by most advanced phase and number of active trials.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
BaricitinibOlumiant®III3NCT04381936
AnakinraKINERETIII2NCT04381936
AspirinVazalore®, Durlaza®III2NCT04381936
Baloxavir MarboxilXofluza®III2NCT04381936
Ceftaroline fosamilCeftaroline, Teflaro®III2NCT02735707
HydroxychloroquineSovuna®, Plaquenil®III2NCT04381936
LevofloxacinLevaquin®, Iquix®II–III2NCT07843017
OseltamivirTamiflu®, Ebilfumin®III2NCT04381936
RemdesivirVekluryIII2NCT07013474
TocilizumabTociluzumab, AvtozmaIII2NCT04381936
AcyclovirSitavig®, Avaclyr®III1NCT06134492
Albuterol SulfateSalbutamol, Proair Respiclick®II–III1NCT06815679
ApremilastOtezla, Apremilast Accord®III1NCT02735707
AzithromycinAzasite®, Zithromax®III1NCT04381936
CeftriaxoneROCEPHIN, Ceftriaxone And Dextrose In Duplex Container®III1NCT02735707

Sorted by most advanced phase and number of active trials. Showing 15 of 49 drugs.

All 63 drugs, with the details

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Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D011014 “Pneumonia”.

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