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Drugs in development · updated 30 October 2026

Apremilast: clinical trials and development status

Other names and codes: Otezla

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 15 January 2015

As of 30 October 2026 Apremilast is in 15 active clinical trials (recruiting or ongoing, phases I–III) for 20 diseases. The most advanced phase is III.

15Active trials
IIIMost advanced phase
20Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Apremilast and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Arthritis, JuvenileIII2NCT04804553
Behcet SyndromeIII2NCT04528082
COVID-19III2NCT02735707
Oral UlcerIII2NCT04528082
Community-acquired pneumoniaIII1NCT02735707
InfluenzaIII1NCT02735707
Lung diseaseIII1NCT02735707
PneumoniaIII1NCT02735707
PsoriasisII–III1NCT06863493
Psoriatic arthritisIII1NCT04908189
Respiratory diseaseIII1NCT02735707
Respiratory tract infectionIII1NCT02735707
AlcoholismII3NCT07029529
Acute respiratory distress syndromeII1NCT04488081
Chronic inducible urticariaII1NCT07850843
Chronic urticariaII1NCT07850843
Epidermolysis bullosa simplexII1NCT06509984
Respiratory InsufficiencyII1NCT04488081
Skin Diseases, GeneticII1NCT06509984
DepressionI1NCT05703685

Everything on Apremilast

In Phuturdex you get every trial with sponsors, countries and dates, development events, FDA and EMA approvals, patents and exclusivities, orphan designations and safety alerts, with PDF and Excel export. Free until 31 March 2027.

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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