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Drugs in development · updated 30 October 2026

Post-Acute COVID-19 Syndrome: drugs in development

As of 30 October 2026 there are 33 active clinical trials (recruiting or ongoing, phases I–III) on 44 drugs for post-Acute COVID-19 Syndrome. 10 are experimental, that is not yet approved in the United States.

33Active trials
10Experimental drugs
1Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
ApabetaloneII–III1NCT06590324
AER002II1NCT05877508
BetahistineII1NCT07567274
CI-581aII1NCT05690503
CI-581bII1NCT05690503
SipavibartKavigale®II1NCT07021794
SonlicromanolII1NCT07298005
VYD2311II1NCT07899346
11C-PS13I1NCT06920628
Kisspeptin 112-121I1NCT07224490

Sorted by most advanced phase and number of active trials.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
MaravirocSelzentry, Celsentri®II–III2NCT06974084
SirolimusRapamycin, Scomara®II–III2NCT04948203
TaurineII–III2NCT06721949
AnakinraKINERETII–III1NCT05926505
AtorvastatinLipitor, Atorvaliq®II–III1NCT06974084
BaricitinibOlumiant®III1NCT06631287
ColchicineColchicin, Lodoco®III1NCT07280572
FluvoxamineLuvox®, Luvox Cr®III1NCT07359482
LosartanArbli®, Cozaar®III1NCT05619653
MetforminRiomet Er®, Glumetza®III1NCT07280572
PirfenidoneEsbriet®, Pirfenidone Viatris®III1NCT06928272
PrednisolonePrednisolon, PrenisoloneIII1NCT05619653
UpadacitinibRinvoq Lq®, Rinvoq®III1NCT06928272
Nogapendekin Alfa InbakiceptN-803, AnktivaII2NCT07123727
AbrocitinibCibinqo®II1NCT06597396

Sorted by most advanced phase and number of active trials. Showing 15 of 34 drugs.

All 44 drugs, with the details

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Broader categories

Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: NLM MeSH; NLM MeSH term: D000094024 “Post-Acute COVID-19 Syndrome”.

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