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Drugs in development · updated 30 October 2026

Sirolimus: clinical trials and development status

Other names and codes: Rapamycin, Scomara, Hyftor, Fyarro, Rapamune

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 13 March 2001

As of 30 October 2026 Sirolimus is in 130 active clinical trials (recruiting or ongoing, phases I–III) for 134 diseases. The most advanced phase is III.

130Active trials
IIIMost advanced phase
134Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Sirolimus and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov. Showing 30 of 134 diseases.

DiseaseMost advanced phaseActive trialsReference trial
Acute myeloid leukemiaII–III9NCT07366801
Precursor lymphoblastic lymphoma/leukemiaII–III8NCT07366801
Breast neoplasmIII3NCT06929325
Lymphatic AbnormalitiesII–III3NCT06673290
NeoplasmII–III3NCT04987463
Systemic lupus erythematosusIII3NCT04582136
EpilepsyII–III2NCT04987463
InfluenzaIII2NCT03901001
Kaposiform hemangioendotheliomaII–III2NCT07656909
Post-Acute COVID-19 SyndromeIII2NCT06960928
Tuberous sclerosisII–III2NCT04987463
Vascular malformationIII2NCT02638389
Autoimmune thrombocytopenic purpuraII–III1NCT07657793
Inclusion body myositisIII1NCT04789070
Kasabach-Merritt syndromeII–III1NCT07656909
LymphangioleiomyomatosisIII1NCT03150914
Pulmonary fibrosisII–III1NCT04948203
Skin neoplasmIII1NCT05860881
Sickle-cell diseaseII16NCT04362293
Myelodysplastic SyndromesII11NCT03970096
Graft-versus-host diseaseII9NCT06799195
Hematologic neoplasmII7NCT06799195
Aplastic anemiaII6NCT02979873
Non-Hodgkin lymphomaII6NCT00544115
Leukemia, Myelogenous, Chronic, BCR-ABL PositiveII5NCT05805605
Multiple myelomaII5NCT00544115
Myeloproliferative disordersII5NCT03970096
Chronic granulomatous diseaseI–II4NCT05463133
Burkitt lymphomaII3NCT00792948
Chronic lymphocytic leukemiaII3NCT05805605

Everything on Sirolimus

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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