Phuturdex › Diseases › Sexually transmitted infection
Drugs in development · updated 30 October 2026
Sexually transmitted infection: drugs in development
As of 30 October 2026 there are 10 active clinical trials (recruiting or ongoing, phases I–III) on 14 drugs for sexually transmitted infection. 6 are experimental, that is not yet approved in the United States.
Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.
Sign in free →Experimental drugs
Not yet approved by the US FDA for any indication.
| Drug | Most advanced phase | Active trials | Reference trial |
|---|---|---|---|
| 4CMenB vaccine | III | 1 | NCT05766904 |
| Ceftriaxone 1000-mg | III | 1 | NCT07710118 |
| Ceftriaxone 500-mg | III | 1 | NCT07710118 |
| Temocillin | III | 1 | NCT07631364 |
| BG505 | I | 1 | NCT05217641 |
| SB-728mR-HSPC | I | 1 | NCT02500849 |
Sorted by most advanced phase and number of active trials.
Approved drugs in new trials
Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.
| Drug | Most advanced phase | Active trials | Reference trial |
|---|---|---|---|
| DoxycyclineDoxycyclin, Lymepak® | II–III | 2 | NCT05897034 |
| AzithromycinAzasite®, Zithromax® | III | 1 | NCT00131235 |
| Bexsero | III | 1 | NCT06446752 |
| CeftriaxoneROCEPHIN, Ceftriaxone And Dextrose In Duplex Container® | III | 1 | NCT07631364 |
| LidocaineXylocaine, Bondlido® | III | 1 | NCT07631364 |
| NitazoxanideAlinia® | II–III | 1 | NCT05897034 |
| Pentoxifyllinepentoxyifylline, Trental® | II–III | 1 | NCT05897034 |
| TinidazoleTindamax® | II | 1 | NCT07088419 |
Sorted by most advanced phase and number of active trials.
All 14 drugs, with the details
In Phuturdex every drug has all its trials, sponsors and countries, FDA and EMA approvals, orphan designations and safety alerts. Free until 31 March 2027.
Open in Phuturdex →Specific forms
- HIV infection 84 drugs
- Acquired Immunodeficiency Syndrome 61 drugs
- Papillomavirus infections 16 drugs
- Kaposi's sarcoma 15 drugs
- Neoplasm 671 drugs
- Infection 71 drugs
- Syphilis 6 drugs
- Oropharyngeal Neoplasms 46 drugs
- Squamous cell carcinoma 72 drugs
- Head and neck neoplasms 184 drugs
- Cardiovascular disease 71 drugs
- HIV seropositivity 4 drugs
Broader categories
- Urogenital Diseases 16 drugs
- Genital Diseases 7 drugs
- Communicable Diseases 12 drugs
- Infection 71 drugs
- Bacterial Infections 16 drugs
- Gram-negative bacterial infection 3 drugs
Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D012749 “Sexually Transmitted Diseases”.