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Drugs in development · updated 30 October 2026

Doxycycline: clinical trials and development status

Other names and codes: Lymepak, Xyrosa, Zenavod, Acticlate Cap

NLM verified identityApproved in the US (FDA)

As of 30 October 2026 Doxycycline is in 29 active clinical trials (recruiting or ongoing, phases I–III) for 46 diseases. The most advanced phase is III.

29Active trials
IIIMost advanced phase
46Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Doxycycline and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov. Showing 30 of 46 diseases.

DiseaseMost advanced phaseActive trialsReference trial
Bacterial vaginosisIII2NCT06349122
Mycobacterium Infections, NontuberculousII–III2NCT04310930
Sexually transmitted infectionIII2NCT07884240
SyphilisIII2NCT07884240
TuberculosisIII2NCT05473520
Acute coronary syndromeIII1NCT05473520
Chlamydia infectionIII1NCT07884240
Communicable DiseasesII–III1NCT05972772
Endemic typhusII–III1NCT05972772
GonorrheaIII1NCT07884240
Lung diseaseII–III1NCT04310930
Premature BirthIII1NCT06349122
Pulmonary hypertensionIII1NCT05473520
Scrub typhusII–III1NCT05972772
Breast neoplasmII2NCT06452394
AcneI–II1NCT02713607
Acneiform eruptionII1NCT07629167
Atopic dermatitisII1NCT01631617
Central nervous system tuberculosisII1NCT06446245
Coronary aneurysmII1NCT01917721
DermatitisII1NCT01631617
EczemaII1NCT01631617
Ehlers-Danlos syndromeI–II1NCT07688096
EmphysemaII1NCT05382208
InfectionII1NCT07485010
Joint dislocationI–II1NCT07688096
Joint instabilityI–II1NCT07688096
Lymphatic AbnormalitiesII1NCT07320001
MeningitisII1NCT06446245
MeningoencephalitisII1NCT06446245

Everything on Doxycycline

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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