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Drugs in development · updated 30 October 2026

Klatskin's tumor: drugs in development

As of 30 October 2026 there are 8 active clinical trials (recruiting or ongoing, phases I–III) on 17 drugs for Klatskin's tumor. 4 are experimental, that is not yet approved in the United States.

8Active trials
4Experimental drugs
3Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
GimeracilIII1NCT06109779
Oteracil Potassium CapsulesIII1NCT06109779
RilvegostomigAZD2936III1NCT06109779
GEMOXGemcitabine-Oxaliplatin RegimenII1NCT05430698

Sorted by most advanced phase and number of active trials.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
CisplatinCis Platinum, CisplatineII–III3NCT06923475
GemcitabineGemcitabin, GemzarII–III3NCT06923475
CapecitabineXeloda, Capectitabine TabletsIII2NCT06109779
PembrolizumabKEYTRUDA, MK-3475II–III1NCT06923475
OxaliplatinOxaliplatine, OxaliplainII2NCT05564403
BinimetinibMEK162, Mektovi®II1NCT05564403
Fluorouracil5-Fluorouracil, AdrucilII1NCT05564403
LeucovorinFolinic acid, l-leucovorinII1NCT05564403
Sacituzumab GovitecanTrodelvy®II1NCT06178588
TislelizumabTisleizumab, TiselizumabII1NCT07030140
ToripalimabJS001, TeripalimabII1NCT06717464
CyclophosphamideCyclophosphamid, CytoxanI1NCT07614061
FludarabineFludara, FLUDARABINI1NCT07614061

Sorted by most advanced phase and number of active trials.

All 17 drugs, with the details

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Broader categories

Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D018285 “Klatskin Tumor”.

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