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Phuturdex › Diseases › Lennox-Gastaut sindrome

Drugs in development · updated 30 October 2026

Lennox-Gastaut sindrome: drugs in development

Rare diseasePrevalence 1-5 / 10 000 according to Orphanet · ORPHA:2382

As of 30 October 2026 there are 5 active clinical trials (recruiting or ongoing, phases I–III) on 4 drugs for lennox-Gastaut sindrome. 4 are experimental, that is not yet approved in the United States.

5Active trials
4Experimental drugs
3Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
LP352III2NCT06908226
CarisbamateComfyde®III1NCT05219617
Clemizole HClEPX-100III1NCT05066217
BMB-101II1NCT06401538

Sorted by most advanced phase and number of active trials.

All 4 drugs, with the details

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Broader categories

Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D065768 “Lennox Gastaut Syndrome”. Prevalence: Orphanet.

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