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Phuturdex › Diseases › Membranoproliferative glomerulonephritis

Drugs in development · updated 30 October 2026

Membranoproliferative glomerulonephritis: drugs in development

Rare diseasePrevalence 1-5 / 10 000 according to Orphanet · ORPHA:54370

As of 30 October 2026 there are 5 active clinical trials (recruiting or ongoing, phases I–III) on 7 drugs for membranoproliferative glomerulonephritis. 3 are experimental, that is not yet approved in the United States.

5Active trials
3Experimental drugs
1Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
IptcaopanIII1NCT05795140
ADX-038II1NCT07522099
TelitaciceptII1NCT07522099

Sorted by most advanced phase and number of active trials.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
IptacopanLNP023, Fabhalta®III1NCT03955445
PegcetacoplanSYFOVRE, Empaveli®III1NCT05809531
AliskirenRasilez®, Riprazo®II1NCT04183101
EnalaprilEpaned®, Aqumeldi®II1NCT04183101

Sorted by most advanced phase and number of active trials.

All 7 drugs, with the details

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Broader categories

Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D015432 “Glomerulonephritis, Membranoproliferative”. Prevalence: Orphanet.

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