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Drugs in development · updated 30 October 2026

Pegcetacoplan: clinical trials and development status

Other names and codes: SYFOVRE, Empaveli, Aspaveli

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 13 December 2021

As of 30 October 2026 Pegcetacoplan is in 9 active clinical trials (recruiting or ongoing, phases I–III) for 13 diseases. The most advanced phase is III.

9Active trials
IIIMost advanced phase
13Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Pegcetacoplan and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
GlomerulonephritisIII1NCT07898774
Membranoproliferative glomerulonephritisIII1NCT05809531
Geographic atrophyII2NCT06722157
Macular degenerationII2NCT06722157
Fallopian tube neoplasmII1NCT04919629
Hemolytic anemiaII1NCT04901936
Ovarian neoplasmII1NCT04919629
Pancreatic neoplasmI–II1NCT07214298
Paroxysmal nocturnal hemoglobinuriaII1NCT04901936
Cerebral infarctionI1NCT07495722
Ischemic strokeI1NCT07495722
Reperfusion injuryI1NCT07495722
ThromboinflammationI1NCT07495722

Everything on Pegcetacoplan

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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