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Drugs in development · updated 30 October 2026

Polycystic Ovary Syndrome: drugs in development

As of 30 October 2026 there are 11 active clinical trials (recruiting or ongoing, phases I–III) on 11 drugs for polycystic Ovary Syndrome. 4 are experimental, that is not yet approved in the United States.

11Active trials
4Experimental drugs
0Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
Alpha Lipoic AcidII1NCT07182526
DihydroartemisininII1NCT06842524
QuercetinII1NCT07182526
MyoinositolI1NCT07459595

Sorted by most advanced phase and number of active trials.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
MetforminRiomet Er®, Glumetza®III4NCT07120815
Clomiphene CitrateSerophene®, Clomid®III2NCT07616973
Letrozoleoral FemaraIII1NCT07616973
SemaglutideWegovy, RybelsusIII1NCT05819853
TamoxifenSoltamox®, Nolvadex®III1NCT07616973
SpironolactoneCarospir®, Aldactone®Early I2NCT04723862
EstradiolESTRING, VagifemEarly I1NCT03401047

Sorted by most advanced phase and number of active trials.

All 11 drugs, with the details

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Broader categories

Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: NLM MeSH; NLM MeSH term: D011085 “Polycystic Ovary Syndrome”.

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