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Drugs in development · updated 30 October 2026

Itacitinib: clinical trials and development status

NLM verified identityNot approved in the USNo EMA authorisation

As of 30 October 2026 Itacitinib is in 8 active clinical trials (recruiting or ongoing, phases I–III) for 14 diseases. The most advanced phase is II.

8Active trials
IIMost advanced phase
14Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Itacitinib and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Myeloproliferative disordersII3NCT05364762
Chronic myelomonocytic leukemiaII2NCT05364762
Myelodysplastic SyndromesII2NCT05364762
Acute myeloid leukemiaII1NCT05364762
Diffuse large B-cell lymphomaII1NCT05757219
Hematologic DiseasesII1NCT04859946
MyelofibrosisII1NCT05364762
Non-Hodgkin lymphomaII1NCT04509700
Precursor lymphoblastic lymphoma/leukemiaII1NCT05364762
Systemic sclerodermaII1NCT04789850
LeukemiaI1NCT05823571
Multiple myelomaI1NCT05823571
Plasma cell leukemiaI1NCT05823571
T-cell prolymphocytic leukemiaI1NCT05823571

Everything on Itacitinib

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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