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Drugs in development · updated 9 November 2026

Milrinone: clinical trials and development status

Other names and codes: Primacor

NLM verified identityApproved in the US (FDA)

As of 9 November 2026 Milrinone is in 3 active clinical trials (recruiting or ongoing, phases I–III) for 3 diseases. The most advanced phase is III.

3Active trials
IIIMost advanced phase
3Diseases studied

Summary updated every week · data as of 9 November 2026. In Phuturdex you can follow Milrinone and get an email at every change or safety alert.

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What it is

A positive inotropic cardiotonic agent with vasodilator properties. It inhibits cAMP phosphodiesterase type 3 activity in myocardium and vascular smooth muscle. Milrinone is a derivative of amrinone and has 20-30 times the inotropic potency of amrinone.

Source: NLM MeSH

Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Heart failureII1NCT05450328
Right ventricular dysfunctionII1NCT05450328
Subarachnoid hemorrhageII1NCT04282629

Everything on Milrinone

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 9 November 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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