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Drugs in development · updated 30 October 2026

N-Acetylcysteine: clinical trials and development status

Other names and codes: Acetadote, Cetylev, Mucomyst

NLM verified identityApproved in the US (FDA)

As of 30 October 2026 N-Acetylcysteine is in 43 active clinical trials (recruiting or ongoing, phases I–III) for 64 diseases. The most advanced phase is III.

43Active trials
IIIMost advanced phase
64Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow N-Acetylcysteine and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov. Showing 30 of 64 diseases.

DiseaseMost advanced phaseActive trialsReference trial
Autism spectrum disorderII–III3NCT05664789
StomatitisIII2NCT07325383
TuberculosisII–III2NCT05686356
Acute kidney injuryII–III1NCT07156786
Alcoholic hepatitisIII1NCT06956482
Aplastic anemiaIII1NCT07737262
Arbovirus InfectionsIII1NCT07543458
Beta thalassemiaIII1NCT07157722
Coronary artery diseaseIII1NCT01878669
Dengue feverIII1NCT07543458
DepressionIII1NCT07464886
Flavivirus InfectionsIII1NCT07543458
Hepatic insufficiencyIII1NCT06956482
InfluenzaIII1NCT03900988
Mosquito-borne diseaseIII1NCT07543458
Neonatal sepsisIII1NCT07380347
NeoplasmII–III1NCT07156786
Retinitis pigmentosaIII1NCT05537220
RNA virus infectious diseaseIII1NCT07543458
Severe DengueIII1NCT07543458
Thrombotic MicroangiopathiesII–III1NCT07279610
Usher SyndromesIII1NCT05537220
Vector-borne diseaseIII1NCT07543458
Viral hemorrhagic feverIII1NCT07543458
Acute myeloid leukemiaII1NCT06024031
Amyotrophic lateral sclerosisI–II1NCT07414212
Breast neoplasmII1NCT07117630
Chronic progressive multiple sclerosisII1NCT05122559
Cognitive dysfunctionI–II1NCT04520139
Cornelia de Lange syndromeII1NCT04381897

Everything on N-Acetylcysteine

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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