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Drugs in development · updated 30 October 2026

Nintedanib: clinical trials and development status

Other names and codes: Vargatef

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 21 November 2014

As of 30 October 2026 Nintedanib is in 11 active clinical trials (recruiting or ongoing, phases I–III) for 11 diseases. The most advanced phase is III.

11Active trials
IIIMost advanced phase
11Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Nintedanib and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Systemic sclerodermaIII2NCT07335562
AdenomyosisIII1NCT07162961
Interstitial lung diseaseIII1NCT06297096
Idiopathic pulmonary fibrosisII3NCT07679893
Non-small-cell lung carcinomaI–II2NCT03377023
Castleman's diseaseII1NCT06643091
EpistaxisII1NCT04976036
FibrosisII1NCT07679893
Hereditary hemorrhagic telangiectasiaII1NCT04976036
Pulmonary fibrosisII1NCT07679893
Acute myeloid leukemiaI1NCT03513484

Everything on Nintedanib

In Phuturdex you get every trial with sponsors, countries and dates, development events, FDA and EMA approvals, patents and exclusivities, orphan designations and safety alerts, with PDF and Excel export. Free until 31 March 2027.

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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