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Drugs in development · updated 30 October 2026

Pelacarsen: clinical trials and development status

NLM verified identityNot approved in the USNo EMA authorisationEstimated launch Apr 2029 – Feb 2030 (Phuturdex estimate)

As of 30 October 2026 Pelacarsen is in 5 active clinical trials (recruiting or ongoing, phases I–III) for 6 diseases. The most advanced phase is III.

5Active trials
IIIMost advanced phase
6Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Pelacarsen and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Cardiovascular diseaseIII3NCT06813911
AtherosclerosisIII2NCT06813911
HyperlipoproteinemiaIII1NCT05900141
Myocardial infarctionIII1NCT07517263
StrokeIII1NCT07517263
Aortic valve stenosisII1NCT05646381

Everything on Pelacarsen

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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