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Drugs in development · updated 30 October 2026

PF-08653944: clinical trials and development status

Development codeNot approved in the USNo EMA authorisationEstimated launch Dec 2028 – Oct 2029 (Phuturdex estimate)

As of 30 October 2026 PF-08653944 is in 6 active clinical trials (recruiting or ongoing, phases I–III) for 11 diseases. The most advanced phase is III.

6Active trials
IIIMost advanced phase
11Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow PF-08653944 and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
ObesityIII5NCT07595549
OverweightIII5NCT07595549
Human body weightIII3NCT07595549
Nutrition disorderIII3NCT07595549
Nutritional and metabolic diseasesIII3NCT07595549
OvernutritionIII3NCT07595549
DiabetesIII2NCT07595549
Endocrine system diseaseIII2NCT07595549
Glucose metabolism diseaseIII2NCT07595549
Metabolic diseaseIII2NCT07595549
Type 2 diabetesIII2NCT07595549

Everything on PF-08653944

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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