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Drugs in development · updated 30 October 2026

Selinexor: clinical trials and development status

Other names and codes: KPT-330, Xpovio

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 26 March 2021

As of 30 October 2026 Selinexor is in 75 active clinical trials (recruiting or ongoing, phases I–III) for 55 diseases. The most advanced phase is III.

75Active trials
IIIMost advanced phase
55Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Selinexor and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov. Showing 30 of 55 diseases.

DiseaseMost advanced phaseActive trialsReference trial
Multiple myelomaIII22NCT07623798
Acute myeloid leukemiaIII10NCT05726110
Diffuse large B-cell lymphomaIII6NCT07011056
MyelofibrosisIII4NCT04562389
Endometrial neoplasmIII2NCT05611931
Myeloproliferative disordersIII2NCT04562389
Extranodal NK/T-cell lymphoma, nasal typeII3NCT07554482
LymphomaII3NCT02436707
NeurofibrosarcomaII2NCT05985161
Ovarian neoplasmII2NCT07832227
Peripheral T-cell lymphomaI–II2NCT07706959
Plasma cell neoplasmII2NCT05597345
SarcomaII2NCT06114004
ThrombocytopeniaII2NCT07447817
Adipose tissue neoplasmI–II1NCT06239272
Alveolar soft part sarcomaII1NCT05333458
AnemiaII1NCT07447817
Angiomatoid fibrous histiocytomaI–II1NCT06239272
B-cell lymphomaI–II1NCT03147885
Breast neoplasmI–II1NCT05035745
CarcinomaII1NCT06813079
Chronic myelomonocytic leukemiaII1NCT06900088
Clear-cell sarcomaI–II1NCT06239272
Dermatofibrosarcoma protuberansI–II1NCT06239272
Disorder of sex developmentI–II1NCT06239272
Epithelioid hemangioendotheliomaI–II1NCT06239272
Extraskeletal myxoid chondrosarcomaI–II1NCT06239272
FibrosarcomaI–II1NCT06239272
Follicular lymphomaI–II1NCT03147885
GlioblastomaI–II1NCT05432804

Everything on Selinexor

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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