PhuturdexDrug Pipeline Intelligence

Phuturdex › Drugs › Tenecteplase

Drugs in development · updated 30 October 2026

Tenecteplase: clinical trials and development status

Other names and codes: Tnkase, Metalyse

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 23 February 2001

As of 30 October 2026 Tenecteplase is in 26 active clinical trials (recruiting or ongoing, phases I–III) for 14 diseases. The most advanced phase is III.

26Active trials
IIIMost advanced phase
14Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Tenecteplase and get an email at every change or safety alert.

Sign in free →

Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Ischemic strokeIII23NCT07906275
StrokeIII12NCT07687056
Brain DiseasesII–III1NCT05105633
Cardiovascular diseaseII–III1NCT05105633
Central nervous system diseaseII–III1NCT05105633
Cerebral hemorrhageIII1NCT06352632
Cerebrovascular diseaseII–III1NCT05105633
Intracranial thrombosisIII1NCT06658197
Myocardial infarctionIII1NCT03998319
Myocardial infarction with ST segment elevationIII1NCT03998319
Nervous System DiseasesII–III1NCT05105633
Vascular diseaseII–III1NCT05105633
Intracranial HemorrhagesII1NCT06781385
ThrombosisII1NCT06781385

Everything on Tenecteplase

In Phuturdex you get every trial with sponsors, countries and dates, development events, FDA and EMA approvals, patents and exclusivities, orphan designations and safety alerts, with PDF and Excel export. Free until 31 March 2027.

Open in Phuturdex →

Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

ItalianoFrançaisDeutsch