Phuturdex › Diseases › Cerebrovascular disease
Drugs in development · updated 30 October 2026
Cerebrovascular disease: drugs in development
As of 30 October 2026 there are 9 active clinical trials (recruiting or ongoing, phases I–III) on 8 drugs for cerebrovascular disease. 5 are experimental, that is not yet approved in the United States.
Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.
Sign in free →Experimental drugs
Not yet approved by the US FDA for any indication.
| Drug | Most advanced phase | Active trials | Reference trial |
|---|---|---|---|
| Dimephosphon | III | 1 | NCT07167550 |
| Retatrutide | III | 1 | NCT06383390 |
| Tegoprazan | III | 1 | NCT07687706 |
| 4D-310 | I–II | 2 | NCT05629559 |
| Nicotinamide ribosideNicotinamide ribonucleoside | I | 1 | NCT06280482 |
Sorted by most advanced phase and number of active trials.
Approved drugs in new trials
Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.
| Drug | Most advanced phase | Active trials | Reference trial |
|---|---|---|---|
| MetforminRiomet Er®, Glumetza® | III | 1 | NCT04511416 |
| TenecteplaseTnkase®, Metalyse® | II–III | 1 | NCT05105633 |
| TocilizumabTociluzumab, Avtozma | III | 1 | NCT04888221 |
Sorted by most advanced phase and number of active trials.
All 8 drugs, with the details
In Phuturdex every drug has all its trials, sponsors and countries, FDA and EMA approvals, orphan designations and safety alerts. Free until 31 March 2027.
Open in Phuturdex →Specific forms
- Ischemic stroke 94 drugs
- Stroke 70 drugs
- Cerebral hemorrhage 23 drugs
- Subarachnoid hemorrhage 14 drugs
- Brain hypoxia-ischemia 14 drugs
- Fabry disease 10 drugs
- Atrial fibrillation 32 drugs
- Giant cell arteritis 30 drugs
- Myocardial infarction 26 drugs
- Cerebral infarction 7 drugs
- Intracranial arteriosclerosis 8 drugs
- Thrombosis 19 drugs
Broader categories
- Brain Diseases 23 drugs
- Central nervous system disease 38 drugs
- Nervous System Diseases 39 drugs
- Vascular disease 16 drugs
- Cardiovascular disease 71 drugs
- Nutritional and metabolic diseases 5 drugs
Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D002561 “Cerebrovascular Disorders”.