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Drugs in development · updated 30 October 2026

Retatrutide: clinical trials and development status

NLM verified identityNot approved in the USNo EMA authorisationEstimated launch Dec 2027 – Oct 2028 (Phuturdex estimate)

As of 30 October 2026 Retatrutide is in 11 active clinical trials (recruiting or ongoing, phases I–III) for 21 diseases. The most advanced phase is III.

11Active trials
IIIMost advanced phase
21Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Retatrutide and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
ObesityIII6NCT07035093
OverweightIII3NCT07035093
Type 2 diabetesIII3NCT06383390
Chronic renal insufficiencyIII2NCT06383390
DiabetesIII2NCT06297603
Endocrine system diseaseIII2NCT06260722
Glucose metabolism diseaseIII2NCT06260722
Kidney diseaseIII2NCT06383390
Metabolic diseaseIII2NCT06260722
AtherosclerosisIII1NCT06383390
Cardiovascular diseaseIII1NCT06383390
Cerebrovascular diseaseIII1NCT06383390
Chronic kidney failureIII1NCT06383390
Coronary artery diseaseIII1NCT06383390
Fatty liver diseaseIII1NCT07165028
Heart diseaseIII1NCT06383390
Non-alcoholic Fatty Liver DiseaseIII1NCT07165028
Peripheral Arterial DiseaseIII1NCT06383390
Human body weightII1NCT07467447
Weight lossII1NCT07467447
Insulin resistanceI1NCT06982859

Everything on Retatrutide

In Phuturdex you get every trial with sponsors, countries and dates, development events, FDA and EMA approvals, patents and exclusivities, orphan designations and safety alerts, with PDF and Excel export. Free until 31 March 2027.

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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