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Drugs in development · updated 30 October 2026

Treosulfan: clinical trials and development status

Other names and codes: Grafapex, Trecondi

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 20 June 2019

As of 30 October 2026 Treosulfan is in 11 active clinical trials (recruiting or ongoing, phases I–III) for 19 diseases. The most advanced phase is II–III.

11Active trials
II–IIIMost advanced phase
19Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Treosulfan and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Myelodysplastic SyndromesII–III3NCT06756152
Precursor lymphoblastic lymphoma/leukemiaII–III3NCT01949129
Acute biphenotypic leukaemiaII–III2NCT06756152
Acute myelomonocytic leukemiaII–III1NCT06756152
Non-Hodgkin lymphomaII–III1NCT06756152
Acute myeloid leukemiaII5NCT07025824
Nijmegen breakage syndromeII2NCT07316595
Anaplastic large-cell lymphomaII1NCT04195633
Burkitt lymphomaII1NCT04195633
Chronic lymphocytic leukemiaII1NCT04195633
Chronic myelomonocytic leukemiaII1NCT04195633
Diffuse large B-cell lymphomaII1NCT04195633
Follicular lymphomaII1NCT04195633
Hodgkin lymphomaII1NCT04195633
Leukemia, Myelogenous, Chronic, BCR-ABL PositiveII1NCT04195633
Lymphoma, B-Cell, Marginal ZoneII1NCT04195633
Mantle cell lymphomaII1NCT04195633
Multiple myelomaII1NCT05636787
Prolymphocytic leukemiaII1NCT04195633

Everything on Treosulfan

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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