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Drugs in development · updated 30 October 2026

Acute lung injury: drugs in development

Rare diseasePrevalence 1-5 / 10 000 according to Orphanet · ORPHA:178320

As of 30 October 2026 there are 8 active clinical trials (recruiting or ongoing, phases I–III) on 9 drugs for acute lung injury. 3 are experimental, that is not yet approved in the United States.

8Active trials
3Experimental drugs
1Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
[18F]FAPI-74III1NCT07613099
AtibuclimabIC14II1NCT06513949
GKL-006RTUI–II1NCT07706855

Sorted by most advanced phase and number of active trials.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
OndansetronZuplenz®, Zofran Odt®II–III1NCT07588217
BaricitinibOlumiant®II1NCT07779642
BelumosudilRezurock®II1NCT06476132
MaravirocSelzentry, Celsentri®II1NCT06853223
PirfenidoneEsbriet®, Pirfenidone Viatris®II1NCT05704166
SimvastatinFlolipid®, Zocor®II1NCT07779642

Sorted by most advanced phase and number of active trials.

All 9 drugs, with the details

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Broader categories

Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D055371 “Acute Lung Injury”. Prevalence: Orphanet.

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