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Drugs in development · updated 30 October 2026

Simvastatin: clinical trials and development status

Other names and codes: Flolipid, Zocor

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 26 August 2013

As of 30 October 2026 Simvastatin is in 27 active clinical trials (recruiting or ongoing, phases I–III) for 32 diseases. The most advanced phase is III.

27Active trials
IIIMost advanced phase
32Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Simvastatin and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov. Showing 30 of 32 diseases.

DiseaseMost advanced phaseActive trialsReference trial
AlcoholismII–III1NCT04971577
Community-acquired pneumoniaIII1NCT02735707
COVID-19III1NCT02735707
FibrosisIII1NCT03654053
Graves' ophthalmopathyIII1NCT03131726
Hepatocellular carcinomaIII1NCT03654053
InfluenzaIII1NCT02735707
Liver cirrhosisII–III1NCT04971577
Lung diseaseIII1NCT02735707
PneumoniaIII1NCT02735707
Respiratory diseaseIII1NCT02735707
Respiratory tract infectionIII1NCT02735707
Sclerosing cholangitisIII1NCT04133792
Acute lung injuryII1NCT07779642
AstrocytomaII1NCT07831369
Biliary tract neoplasmII1NCT07003815
Breast neoplasmII1NCT03324425
CardiomyopathiesII1NCT06632834
Dilated cardiomyopathyII1NCT06632834
Esophageal neoplasmII1NCT07625930
GlioblastomaII1NCT07831369
LeiomyomaII1NCT03400826
MetastasisII1NCT05821556
Pancreatic neoplasmI–II1NCT06030622
Prostatic NeoplasmsII1NCT05586360
Triple-negative breast neoplasmII1NCT05550415
XanthomatosisII1NCT07662785
DiabetesI1NCT07378293
Chronic pancreatitisEarly I1NCT05771675
LymphomaEarly I1NCT04514029

Everything on Simvastatin

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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