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Drugs in development · updated 30 October 2026

[18F]FAPI-74: clinical trials and development status

FDA substance registryNot approved in the USNo EMA authorisationEstimated launch Oct 2028 – Aug 2029 (Phuturdex estimate)

As of 30 October 2026 [18F]FAPI-74 is in 9 active clinical trials (recruiting or ongoing, phases I–III) for 29 diseases. The most advanced phase is III.

9Active trials
IIIMost advanced phase
29Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow [18F]FAPI-74 and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Stomach neoplasmIII4NCT07217704
Acute lung injuryIII1NCT07613099
Arterial pulmonary hypertensionIII1NCT07613099
Cardiovascular diseaseIII1NCT07613099
Esophageal neoplasmIII1NCT07217704
Interstitial lung diseaseIII1NCT07613099
Breast neoplasmII2NCT07285993
Hepatocellular carcinomaII2NCT06503146
MesotheliomaII2NCT06503146
Bladder neoplasmII1NCT06503146
CholangiocarcinomaII1NCT06503146
EndometriosisI–II1NCT07705074
Head and neck neoplasmsI–II1NCT07705074
Lung small cell carcinomaII1NCT06503146
MetastasisII1NCT07285993
Multiple myelomaI–II1NCT07705074
Ovarian neoplasmII1NCT06503146
Pancreatic cancer, adultI–II1NCT07705074
ParagangliomaII1NCT06503146
PheochromocytomaII1NCT06503146
PlasmacytomaI–II1NCT07705074
Prostatic NeoplasmsI–II1NCT07705074
Pulmonary fibrosisI–II1NCT07705074
SarcoidosisI–II1NCT07705074
SarcomaII1NCT06503146
Thyroid neoplasmI–II1NCT07705074
Transitional cell carcinomaI–II1NCT07705074
Pulmonary tuberculosisEarly I1NCT07830771
TuberculosisEarly I1NCT07830771

Everything on [18F]FAPI-74

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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