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Drugs in development · updated 30 October 2026

Pheochromocytoma: drugs in development

As of 30 October 2026 there are 25 active clinical trials (recruiting or ongoing, phases I–III) on 29 drugs for pheochromocytoma. 14 are experimental, that is not yet approved in the United States.

25Active trials
14Experimental drugs
0Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
177Lu-DOTATOCLutetium Lu 177-EdotreotideII1NCT06045260
[18F]FAPI-74II1NCT06503146
AnlotinibAL3818, AnrotinibII1NCT06429397
BenmelstobartTQB2450II1NCT06429397
DotatateII1NCT04711135
Ga-68-DOTATATEII1NCT03206060
HTL0039732I–II1NCT05944237
IvocizumabII1NCT06683846
IvonescimabAK112II1NCT07743138
Lu-177-DOTATATEII1NCT03206060
TipifarnibII1NCT04284774
ZanzalintinibXL092II1NCT07714551
ADCT-701I1NCT06041516
18F-MFBGEarly I1NCT05069220

Sorted by most advanced phase and number of active trials.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
68Ga-DOTATATEGallium 68 Dotatate, Gallium Ga 68-DOTATATEI–II3NCT06427798
BelzutifanWelireg®II3NCT04924075
LutatheraLutetium Lu 177 Dotatate, 177Lu-DOTATATEI–II2NCT06607692
OlaparibAZD2281, Lynparza®I–II2NCT06607692
18F-FDG^1^8F-fluorodeoxyglucose, Fludeoxyglucose F-18II1NCT06503146
AtezolizumabTecentriq, MPDL3280AI–II1NCT05944237
AxitinibInlyta®, Axitinib Accord®II1NCT03839498
Iobenguane I 131Azedra®II1NCT00107289
IpilimumabYERVOY, ipililumab IVII1NCT02834013
LanreotideSomatuline Depot®II1NCT03946527
NivolumabOpdivo, ONO-4538II1NCT02834013
PembrolizumabKEYTRUDA, MK-3475II1NCT02721732
TemozolomideTemodal, TemodarII1NCT04394858
CyclophosphamideCyclophosphamid, CytoxanI1NCT04119024
FludarabineFludara, FLUDARABINI1NCT04119024

Sorted by most advanced phase and number of active trials.

All 29 drugs, with the details

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Broader categories

Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: NLM MeSH; NLM MeSH term: D010673 “Pheochromocytoma”.

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