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Phuturdex › Diseases › Epidermolysis bullosa dystrophica

Drugs in development · updated 30 October 2026

Epidermolysis bullosa dystrophica: drugs in development

Rare diseasePrevalence 1-9 / 1 000 000 according to Orphanet · ORPHA:303

As of 30 October 2026 there are 8 active clinical trials (recruiting or ongoing, phases I–III) on 8 drugs for epidermolysis bullosa dystrophica. 7 are experimental, that is not yet approved in the United States.

8Active trials
7Experimental drugs
3Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
EB-101III1NCT05725018
FCX-007III1NCT04213261
KB803III1NCT07016750
AGLE-102I–II1NCT04173650
Intravenous immune globulin GImmunoglobulin GI–II1NCT06834035
TCP-25II1NCT06594393
ELK-003I1NCT06713434

Sorted by most advanced phase and number of active trials.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
Efgartigimod IVEfgartigimod Alfa, Vyvgart®I–II1NCT07011589

Sorted by most advanced phase and number of active trials.

All 8 drugs, with the details

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Broader categories

Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D016108 “Epidermolysis Bullosa Dystrophica”. Prevalence: Orphanet.

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