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Drugs in development · updated 30 October 2026

Efgartigimod IV: clinical trials and development status

Other names and codes: Vyvgart

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 10 August 2022

As of 30 October 2026 Efgartigimod IV is in 16 active clinical trials (recruiting or ongoing, phases I–III) for 13 diseases. The most advanced phase is III.

16Active trials
IIIMost advanced phase
13Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Efgartigimod IV and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Myasthenia gravisIII7NCT06765161
Autoimmune thrombocytopenic purpuraIII2NCT06544499
Guillain–Barré syndromeII–III1NCT06885762
Anti-N-Methyl-D-Aspartate Receptor EncephalitisII1NCT07822776
Autoimmune disease of the nervous systemII1NCT07822776
Epidermolysis bullosaI–II1NCT07011589
Epidermolysis bullosa acquisitaI–II1NCT07011589
Epidermolysis bullosa dystrophicaI–II1NCT07011589
Immunoglobulin G4-Related DiseaseII1NCT07025330
Multiple sclerosisII1NCT06453694
Neuromyelitis opticaII1NCT06453694
Optic neuritisII1NCT06453694
Stiff-person syndromeII1NCT06528392

Everything on Efgartigimod IV

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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