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Drugs in development · updated 30 October 2026

Immunoglobulin G4-Related Disease: drugs in development

As of 30 October 2026 there are 16 active clinical trials (recruiting or ongoing, phases I–III) on 14 drugs for immunoglobulin G4-Related Disease. 9 are experimental, that is not yet approved in the United States.

16Active trials
9Experimental drugs
2Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
IMM0306II–III1NCT07621939
ObexelimabIII1NCT05662241
ACE1831I–II1NCT07061938
FilgotinibJyseleca®II1NCT06285539
FKC289I1NCT06285279
CD19Early I1NCT07298590
PRG-1801Early I1NCT06497387
PRG-2311Early I1NCT06497361
V001-BCMAEarly I1NCT07339540

Sorted by most advanced phase and number of active trials.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
InebilizumabUplizna®III2NCT04540497
LenalidomideRevlimid, lenalinomideII–III2NCT07068165
PrednisonePredinisone, CortancylII–III2NCT07068165
RilzabrutinibWayrilz®III1NCT07190196
Efgartigimod IVEfgartigimod Alfa, Vyvgart®II1NCT07025330

Sorted by most advanced phase and number of active trials.

All 14 drugs, with the details

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Broader categories

Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: NLM MeSH; NLM MeSH term: D000077733 “Immunoglobulin G4-Related Disease”.

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