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Drugs in development · updated 30 October 2026

Myasthenia gravis: drugs in development

Rare diseasePrevalence 1-9 / 100 000 according to Orphanet · ORPHA:589

As of 30 October 2026 there are 61 active clinical trials (recruiting or ongoing, phases I–III) on 49 drugs for myasthenia gravis. 27 are experimental, that is not yet approved in the United States.

61Active trials
27Experimental drugs
7Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
ClaseprubartIII2NCT07647510
TelitaciceptIII2NCT06456580
B007II–III1NCT06447597
CemdisiranIII1NCT05070858
Decartes-08III1NCT06799247
IMVT-1402III1NCT07039916
KYV-101II–III1NCT06193889
Empasiprubart IVARGX-117II2NCT07673627
AritinerceptI–II1NCT07596901
CABA-201I–II1NCT06359041
CNP-106I–II1NCT06106672
Descartes-08II1NCT04146051
NMD670II1NCT06414954
PovetaciceptII1NCT07501702
RipertamabI–II1NCT07372807
SHR-2173II1NCT07622342
YTB323I–II1NCT06704269
CD20I2NCT07676266
GC012FI2NCT06759948
CC-97540I1NCT06220201
CD19-BCMAI1NCT06371040
CizutamigI1NCT07215650
HN2301I1NCT07556120
KITE-363I1NCT07304154
SYS6020I1NCT06688435
CD19Early I1NCT07337785
QT-019CEarly I1NCT07392528

Sorted by most advanced phase and number of active trials.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
Efgartigimod IVEfgartigimod Alfa, Vyvgart®II–III7NCT04833894
NipocalimabM281, Imaavy®II–III3NCT05265273
RozanolixizumabRystiggo®III3NCT06540144
ZilucoplanZilbrysq®II–III3NCT06055959
InebilizumabUplizna®III2NCT04524273
RavulizumabUltomiris®III2NCT07596784
BlinatumomabBlincyto®II–III1NCT06836973
Cladribine2-chlorodeoxyadenosine, Mavenclad®III1NCT06463587
IptacopanLNP023, Fabhalta®III1NCT06517758
PozelimabVeopoz®III1NCT05070858
RemibrutinibLOU064, Rhapsido®III1NCT06744920
RituximabRuxience, RituxanIII1NCT06342544
Anti-Thymocyte GlobulinII1NCT00716066
CarmustineBCNU, BiCNUII1NCT00716066
CytarabineAra-C, Cytosine ArabinosideII1NCT00716066

Sorted by most advanced phase and number of active trials. Showing 15 of 22 drugs.

All 49 drugs, with the details

In Phuturdex every drug has all its trials, sponsors and countries, FDA and EMA approvals, orphan designations and safety alerts. Free until 31 March 2027.

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Broader categories

Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D009157 “Myasthenia Gravis”. Prevalence: Orphanet.

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