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Drugs in development · updated 30 October 2026

Cladribine: clinical trials and development status

Other names and codes: 2-chlorodeoxyadenosine, Mavenclad, Leustatin, Litak, Movectro

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 14 April 2004

As of 30 October 2026 Cladribine is in 33 active clinical trials (recruiting or ongoing, phases I–III) for 20 diseases. The most advanced phase is III.

33Active trials
IIIMost advanced phase
20Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Cladribine and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Acute myeloid leukemiaII–III17NCT04708054
Myelodysplastic SyndromesII–III6NCT04708054
Hairy cell leukemiaII–III5NCT02131753
Multiple sclerosisIII3NCT03477500
Chronic myelomonocytic leukemiaII–III2NCT04708054
Chronic progressive multiple sclerosisII–III2NCT04695080
Langerhans-cell histiocytosisII–III1NCT02205762
Myasthenia gravisIII1NCT06463587
Acute biphenotypic leukaemiaII4NCT02115295
Blast CrisisII2NCT03589729
LeukemiaII2NCT00923013
Myeloid sarcomaII2NCT03589729
Acute monocytic leukemiaII1NCT06504459
Leukemia, Myelogenous, Chronic, BCR-ABL PositiveII1NCT02115295
Myeloproliferative disordersII1NCT03589729
Relapsing-remitting multiple sclerosisII1NCT07517185
Residual neoplasmII1NCT00923013
T-cell prolymphocytic leukemiaI–II1NCT07311746
Burkitt lymphomaI1NCT06060782
Precursor lymphoblastic lymphoma/leukemiaI1NCT06060782

Everything on Cladribine

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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