Phuturdex › Diseases › Hearing Loss
Drugs in development · updated 30 October 2026
Hearing Loss: drugs in development
As of 30 October 2026 there are 12 active clinical trials (recruiting or ongoing, phases I–III) on 13 drugs for hearing Loss. 4 are experimental, that is not yet approved in the United States.
Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.
Sign in free →Experimental drugs
Not yet approved by the US FDA for any indication.
| Drug | Most advanced phase | Active trials | Reference trial |
|---|---|---|---|
| Ebselen | III | 2 | NCT06859788 |
| AC102 gel | II | 1 | NCT05776459 |
| ORC-13661 | II | 1 | NCT05730283 |
| TributyrinGlycerol Tributyrate | I–II | 1 | NCT06792500 |
Sorted by most advanced phase and number of active trials.
Approved drugs in new trials
Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.
| Drug | Most advanced phase | Active trials | Reference trial |
|---|---|---|---|
| Isosorbide oral solutionIsmotic® | II–III | 1 | NCT06765993 |
| MethylprednisoloneMethylprednisolon, Methylprenisolone | III | 1 | NCT05851508 |
| Sodium Thiosulfatetiosulfate, Pedmark® | II | 2 | NCT05129748 |
| AtorvastatinLipitor, Atorvaliq® | II | 1 | NCT04915183 |
| Clemastine FumarateTavist-1®, Tavist® | I–II | 1 | NCT07304024 |
| MannitolD-Mannitol, Bronchitol® | II | 1 | NCT05129748 |
| PrednisolonePrednisolon, Prenisolone | II | 1 | NCT05776459 |
| CisplatinCis Platinum, Cisplatine | I | 1 | NCT07218913 |
| LidocaineXylocaine, Bondlido® | Early I | 1 | NCT04192773 |
Sorted by most advanced phase and number of active trials.
All 13 drugs, with the details
In Phuturdex every drug has all its trials, sponsors and countries, FDA and EMA approvals, orphan designations and safety alerts. Free until 31 March 2027.
Open in Phuturdex →Specific forms
- Sudden sensorineural hearing loss 5 drugs
- Retinitis pigmentosa 25 drugs
- Usher Syndromes 5 drugs
- Sensorineural hearing loss 8 drugs
- Hidden hearing loss 4 drugs
- Diabetes 91 drugs
- Ototoxicity 3 drugs
- Mitochondrial disease 10 drugs
- MELAS syndrome 3 drugs
- Deafness 3 drugs
- Cone-rod dystrophy 5 drugs
- Retinal degeneration 15 drugs
Broader categories
- Nervous System Diseases 39 drugs
- Neurologic Manifestations 15 drugs
- Otorhinolaryngologic disease 4 drugs
- Ear disease 4 drugs
- Neoplasm 671 drugs
- Brain Diseases 23 drugs
Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: NLM MeSH; NLM MeSH term: D034381 “Hearing Loss”.