Phuturdex › Diseases › Heart valve disease
Drugs in development · updated 30 October 2026
Heart valve disease: drugs in development
As of 30 October 2026 there are 2 active clinical trials (recruiting or ongoing, phases I–III) on 3 drugs for heart valve disease. 0 are experimental, that is not yet approved in the United States.
Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.
Sign in free →Approved drugs in new trials
Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.
| Drug | Most advanced phase | Active trials | Reference trial |
|---|---|---|---|
| ApixabanEliquis, Abanta® | III | 1 | NCT07434661 |
| Protamine sulfate | III | 1 | NCT06215378 |
| WarfarinPanwarfin®, Athrombin-K® | III | 1 | NCT07434661 |
Sorted by most advanced phase and number of active trials.
All 3 drugs, with the details
In Phuturdex every drug has all its trials, sponsors and countries, FDA and EMA approvals, orphan designations and safety alerts. Free until 31 March 2027.
Open in Phuturdex →Specific forms
- Hypertrophic cardiomyopathy 16 drugs
- Aortic valve stenosis 13 drugs
- Heart failure 104 drugs
- Cardiovascular disease 71 drugs
- Aortic valve disease 4 drugs
- Aortic valve calcification 3 drugs
- Hyperlipoproteinemia Type II 12 drugs
- Hypercholesterolemia 21 drugs
- Hyperlipidemia 26 drugs
- Dyslipidemia 35 drugs
- Cardiomyopathies 23 drugs
- Left ventricular hypertrophy 4 drugs
Broader categories
- Cardiovascular disease 71 drugs
- Heart disease 17 drugs
- Arrhythmias, Cardiac 10 drugs
- Aortic valve disease 4 drugs
Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D006349 “Heart Valve Diseases”.