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Drugs in development · updated 30 October 2026

In situ carcinoma: drugs in development

As of 30 October 2026 there are 8 active clinical trials (recruiting or ongoing, phases I–III) on 10 drugs for in situ carcinoma. 4 are experimental, that is not yet approved in the United States.

8Active trials
4Experimental drugs
1Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
TARA-002III2NCT07480356
EG-70I–II1NCT04752722
Intismeran autogenemRNA-4157II1NCT06833073
ONM-501I1NCT06022029

Sorted by most advanced phase and number of active trials.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
GemcitabineGemcitabin, GemzarII2NCT07189793
Aminolevulinic Acid5-Aminolevulinic acid Hydrochloride, GliolanII1NCT06876038
DocetaxelTaxotere, Beizray®II1NCT07322263
Mitomycin CMitomycin, JelmytoII1NCT07189793
ToripalimabJS001, TeripalimabII1NCT07189793
CemiplimabREGN2810, Libtayo®I1NCT06022029

Sorted by most advanced phase and number of active trials.

All 10 drugs, with the details

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Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D002278 “Carcinoma in Situ”.

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