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Drugs in development · updated 30 October 2026

Kidney Calculi: drugs in development

As of 30 October 2026 there are 11 active clinical trials (recruiting or ongoing, phases I–III) on 11 drugs for kidney Calculi. 4 are experimental, that is not yet approved in the United States.

11Active trials
4Experimental drugs
0Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
YOLT-203II2NCT07587021
TRA16II1NCT07871669
Ketorolac TrometamolEarly I1NCT03638999
MTP-CP101Early I1NCT05516472

Sorted by most advanced phase and number of active trials.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
EmpagliflozinJardianceIII2NCT06653738
FurosemideLasix Onyu®, Furoscix®III1NCT05916963
Sodium BicarbonateSodium Bicarbonate In Plastic Container®I–II2NCT07408076
ChlorthalidoneHemiclor®, Thalitone®II1NCT06111885
HydrochlorothiazideInzirqo®, Microzide®II1NCT06111885
IndapamideLozol®II1NCT06111885
VancomycinTyzavan®, Firvanq Kit®Early I1NCT05516472

Sorted by most advanced phase and number of active trials.

All 11 drugs, with the details

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Broader categories

Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: NLM MeSH; NLM MeSH term: D007669 “Kidney Calculi”.

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