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Drugs in development · updated 30 October 2026

Hydrochlorothiazide: clinical trials and development status

Other names and codes: Inzirqo, Microzide, Oretic, Hydrodiuril

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 14 October 1998

As of 30 October 2026 Hydrochlorothiazide is in 5 active clinical trials (recruiting or ongoing, phases I–III) for 10 diseases. The most advanced phase is III.

5Active trials
IIIMost advanced phase
10Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Hydrochlorothiazide and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Autosomal dominant polycystic kidneyIII1NCT05373264
Heart failureII–III1NCT07469722
PolyuriaIII1NCT05373264
Kidney CalculiII1NCT06111885
NephrolithiasisII1NCT06111885
DiabetesI1NCT04934228
Insulin resistanceI1NCT04934228
ObesityI1NCT04934228
Arterial hypertensionEarly I1NCT04676399
Chronic painEarly I1NCT04676399

Everything on Hydrochlorothiazide

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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