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Drugs in development · updated 30 October 2026

Empagliflozin: clinical trials and development status

Other names and codes: Jardiance

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 22 May 2014

As of 30 October 2026 Empagliflozin is in 75 active clinical trials (recruiting or ongoing, phases I–III) for 58 diseases. The most advanced phase is III.

75Active trials
IIIMost advanced phase
58Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Empagliflozin and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov. Showing 30 of 58 diseases.

DiseaseMost advanced phaseActive trialsReference trial
Heart failureIII11NCT06424288
Type 2 diabetesIII9NCT07064473
Cardiovascular diseaseIII4NCT07064473
Chronic kidney failureIII3NCT05715814
Chronic renal insufficiencyIII3NCT06531824
Metabolic syndromeIII3NCT07065357
Arterial hypertensionIII2NCT07064473
Insulin resistanceIII2NCT06894784
Kidney CalculiIII2NCT06653738
NephrolithiasisIII2NCT06653738
Cardio-Renal SyndromeII–III1NCT06030843
Cardiogenic shockIII1NCT05879276
CardiotoxicityIII1NCT05271162
Community-acquired pneumoniaIII1NCT04381936
Congenital heart diseaseIII1NCT06955260
COVID-19III1NCT04381936
Cystic fibrosisII–III1NCT06149793
DyslipidemiaIII1NCT04602754
Foreign body granulomaII–III1NCT07828002
HypercalcemiaII–III1NCT07828002
Hypertrophic cardiomyopathyIII1NCT05182658
NephrocalcinosisII–III1NCT07828002
Nephrotic syndromeII–III1NCT07214818
PneumoniaIII1NCT04381936
ProteinuriaII–III1NCT07214818
Type-1 diabetesIII1NCT06894784
Myocardial infarction with ST segment elevationII3NCT07898709
ObesityII3NCT06745063
AlbuminuriaII2NCT07175051
Breast neoplasmII2NCT07883512

Everything on Empagliflozin

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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